Distribution of tiger in the core area of the Manas Tiger Reserve is not uniform in any part of the habitation. The distribution of tiger in the core area i.e. Manas National Park is mainly dependent on the availability of prey species in a particular area. The distribution of the tiger in the Manas National Park fluctuates with the fluctuating population of the prey. However, It has been observed that in certain areas of the tiger bearing landscape usually has the higher density of tiger than the other areas. Such higher density area has several habitat characteristics, which is favourable for the tiger for its survival. The higher density areas are the Hakua river bed, Mathanguri area, Garuchara area, Sukanjan area, Gundabeel area, Kalpani area, Rabang, Garuchara, Doimari, Alabari areas. The areas with the low-density are: the Buraburi-jhar, Second gate, Makhibaha, Semajhora, Teklai, Latajhar, Narayanguri and Panda camp area etc.
The leopard in Manas National Park is very unique with its less distribution in the areas of higher distribution of tiger. The distribution of leopard is more in the southern boundary of the Manas National Park. The distribution of the leopard is found to be more in the secondary vegetation growth area near the fringe of the national park with the villages where abundant domesticated cattle enter regularly. The higher density distribution area of the leopard are the Lafasari, Kuhighat, Sidajhar, Narayanguri, Manas & Hakua river bed lower side, Pahufield, Khoirbari, Palsiguri, Buraburhijhar, Uchila, Makhibaha, Tangonmara, Teklai etc. However, though leopard existed in the entire national park area still the low density of leopard is observed in the areas like Mathanguri, Sukhanjan, Gabharukhunada, Garuchara, Rabang, Doimari, Kalpani, Chorfuli, Roisinglajhar.