Manas Tiger Reserve is developing into an excellent research centre due to its rich flora and fauna and diverse habitat. In mid-eighties, before the civil agitation, study initiated by the Botanical Survey of India (BSI) and the Bombay Natural History Society (BNHS) on Bengal Florican was the beginning of the scientific research in the NP.

In 1995, Pygmy Hog Conservation Programme started under a MoU between Govt. of Assam, Govt. of India, Pigs, Peccaries and Hippo Specialist Group of IUCN and the Durrell Wildlife Trust, UK. Since inception of the programme, regular studies have been carried out on the Pygmy hog (Porcula salvania) and grassland ecology in the park.

The Manas National Park has been a living laboratory for academicians of numbers of Indian University.

Under World Heritage Biodiversity Programme, ATREE ( an NGO) is conducting research on vegetation succession, especially on grassland. Aaranyak, a scientific and industrial research organization has been involved in carrying out number research works. Some of the keys are Manas Tiger Reserve Information System- a GIS-based database, monitoring of elephant population using dung count, human-elephant conflict monitoring, monitoring of Bengal florican, swamp deer, hog deer and the hispid hare. Aaranyak and WWF-India are involved in carrying out monitoring and habitat utilization pattern of translocated rhinos using GPS based radio telemetry. Aaranyak, WWF-India, and ATREE in collaboration in park authorities have been regularly conducting the monitoring of tiger and its prey in the park since 2008.